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Randomized study of clinical effect of enteral nutrition support during neoadjuvant chemotherapy on chemotherapy-related toxicity in patients with esophageal cancer

Hiroshi Miyata, Masahiko Yano, Takushi Yasuda, Rie Hamano, Makoto Yamasaki, Eihou Hou, Masaaki Motoori, Osamu Shiraishi, Koji Tanaka, Masaki Mori, Yuichiro Doki

Clinical Nutrition Volume 31, Issue 3, June 2012, Pages 330–336

Editors' comments: Dr. A.Snegovoy

Nutritional support is an integral part of the supportive care of cancer patients. To date, the different countries have their own recommendations for its implementation. However, studies are risen on the effects of nutritional support on the toxicity of chemotherapy is not much and common relate to the role of parenteral nutrition .
The role of enteral nutrition in oncology is clearly underestimate, although it is known that the intestine is the same as the critical organ and the heart, besides it performs a variety of necessary functions.
Reduction in the incidence of gastrointestinal toxicity on the background of enteral nutrition in patients receiving chemotherapy, to date is shown in several published articles. The question of the influence of enteral nutrition on hematologic toxicity insufficiently studied. In this article convincingly demonstrated the positive role of enteral nutrition in reducing hematologic toxicity during chemotherapy, which can be used in clinical practice.