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Symptomatic Toxicities Experienced During Anticancer Treatment: Agreement Between Patient and Physician Reporting in Three Randomized Trials

Massimo Di Maio, Ciro Gallo, Natasha B. Leighl et al.

Published online before print January 26, 2015, doi: 10.1200/JCO.2014.57.9334

Editors’ comment: Dr. Ricardo Caponero

It is well known that physicians under-report adverse events. This paper describes the disagreement between patient and physician reporting in three randomized trials and shows again our difficulty in adequately recording patient’s symptoms. This work reinforces the necessity of patient-reported outcomes as a standard method to evaluate adverse events in and outside clinical trials.

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