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Management of Chemotherapy Extravasation: ESMO Clinical Practice Guidelines
J. A. Pérez Fidalgo, L. García Fabregat, A. Cervantes, A. Margulies, C. Vidall, F. Roila on behalf of the ESMO Guidelines Working Group
Annals of Oncology 2012; 23(Supplement 7): vii167–vii173
Extravasation is the process by which any liquid (fluid or drug) accidentally leaks into the surrounding tissue. In terms of cancer therapy, extravasation refers to the inadvertent infiltration of chemotherapy into the subcutaneous or subdermal tissues surrounding the intravenous or intra-arterial administration site.