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SIOG Clinical Guidelines on Breast Cancer in the Elderly (2007)

Hans Wildiers, Matti Aapro, Riccardo A. Audisio, Harry Bartelink, Mary Barton, Chantal Bernard-Marty, Laura Biganzoli, Etienne Brain, Martine Extermann Jacques Fracheboud, Sharon H. Giordano, Véronique Girre, Arti Hurria, Ian Kunkler, Hyman Muss Georges,

The International Society of Geriatric Oncology (in French ‘Société Internationale d’Oncologie Gériatrique’, hence SIOG) was founded in recognition of the major epidemiologic challenge that lies before us: The world’s aging population in light of the fact that age is one of the major risk factors for cancer. SIOG's main goal is to improve the care of older patients with cancer around the world.

The SIOG Breast Cancer in the Elderly Task Force did an extensive review of 18 year of breast cancer literature in 2007, leading to a paper in The Lancet Oncology on the management of breast cancer in elderly individuals (Lancet Oncol 2007; 8:1101-15). This study was expanded and updated by a joint SIOG and European Society of Breast Cancer Specialists (EUSOMA) Task Force in 2010. The update was published in The Lancet Oncology in 2012 (Lancet Oncol 2012; 13:e148-60).

In these two articles the Task Force provides recommendations for screening, surgery, radiotherapy, (neo)adjuvant hormone treatment and chemotherapy, metastatic disease, geriatric assessment, competing causes of mortality, ductal carcinoma in situ, drug safety and compliance, patient preferences, barriers to treatment, and male breast cancer. It should be noted that only few large clinical trials in elderly patients with breast cancer are available. The Task Force used its best efforts to extract reliable information to support consensus recommendations on the care of elderly breast cancer patients.

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