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Amgen Symposium: fatigue and physical activity

By Laurent Zelek, recorded at TAO (Transatlantic Oncology meeting), Nov 20-21, 2014, Paris

24 - Laurent Zelek ANG

It almost seems an oxymoron to treat fatigue with physical activity – normally, people who are tired should get some rest. However, after the elimination of other causes of fatigue, such as anemia or endocrine diseases, physical exercise is the only intervention for which an impact on fatigue has been shown. Even though fatigue, depression and cognitive disorders are linked, tests with antidepressants have demonstrated that chronic fatigue in oncology is not a hidden depression. The underlying mechanism of chronic fatigue is not fully known, but some predictors, e.g. pre-treatment fatigue oder overweight, can help to identify the patients at a higher risk of fatigue.


Laurent Zelek, Hôpital Avicennes, Bobigny, France

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