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Session on Cardio-nephrology: renal toxicities
By Eric P. Cohen, recorded at TAO (Transatlantic Oncology meeting), Nov 20-21, 2014, Paris
Collaboration between oncologists and nephrologists is important in the renal field, as there is a bidirectional association. On the one hand, the kidney can have an impact on cancer and its treatment: it has been shown, for example, that the incidence of cancer increases after kidney transplantation. Besides, impaired renal function may require dose reductions, and some drugs are contraindicated in renal failure. However, as most clinical trials exclude patients with chronic renal failure, there is a lack of data in this field. On the other hand, cancer can have an impact on the kidneys (for example, kidney cancer or paraneoplastic syndrome), while cancer treatment can induce renal toxicities. Eric P. Cohen reviews this interaction, also discussing the glomerular filtration rate.
Eric P. Cohen, Medical College of Wisconsin, Milwaukee, USA